Characteristics of the arthropathy described in hereditary hemochromatosis
نویسندگان
چکیده
منابع مشابه
Characteristics of the arthropathy described in hereditary hemochromatosis.
Hereditary hemochromatosis (HH) is a common inherited metabolic disorder characterized by systemic iron overload (1,2). HH affects approximately 1 in 200 people and is most common in persons of Northern European origin. Organ damage in the pancreas, liver, heart, endocrine glands, skin, and joints has been described in HH. There is evidence that the frequency and extent of organ damage may be c...
متن کاملHereditary hemochromatosis.
Hereditary hemochromatosis is definitively diagnosed based on liver biopsy findings.
متن کاملHereditary hemochromatosis.
Hereditary hemochromatosis is an autosomal recessive disorder that disrupts the body's regulation of iron. It is the most common genetic disease in whites. Men have a 24-fold increased rate of iron-overload disease compared with women. Persons who are homozygous for the HFE gene mutation C282Y comprise 85 to 90 percent of phenotypically affected persons. End-organ damage or clinical manifestati...
متن کاملHereditary hemochromatosis
of terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted noncommercial use, distribution, and reproduction in any medium provided article is properly cited. a Department of Pathology and Laboratory Medicine David Geffen School of Medicine University of California, Los Angeles/CA USA. b Department of Pathology and Laboratory Medicine Weill Cornell Medical Co...
متن کاملHereditary hemochromatosis is characterized by a clinically definable arthropathy that correlates with iron load.
OBJECTIVE To determine the frequency and character of arthropathy in hereditary hemochromatosis (HH) and to investigate the relationship between this arthropathy, nodal interphalangeal osteoarthritis, and iron load. METHODS Participants were recruited from the community by newspaper advertisement and assigned to diagnostic confidence categories for HH (definite/probable or possible/unlikely)....
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ژورنال
عنوان ژورنال: Arthritis Care & Research
سال: 2011
ISSN: 2151-464X
DOI: 10.1002/acr.20501